Scientists from the University of Queensland, Australia, have discovered a new type of dual stem cells (SC) that can produce tissues with integrated blood vessels. The results of the study are published in Stem Cell Reports.
Scientists from the University of Pennsylvania, US, have studied the regenerative properties of gingival stem cells that play a role in accelerated wound healing. Their findings, published March 14, 2018 in Science Translational Medicine, point the way forward for therapeutic strategies aimed at treating delayed wounds, as well as other conditions that that involve an overactive inflammatory response, such as autoimmune diseases.
Scientists from the Stanford University School of Medicine, US, have developed an anti-cancer vaccine based on induced pluripotent stem cells (iPSCs). The results, published in Cell Stem Cell, show that vaccinating people with their own iPS cells from many cancers can become a reality in the near future.
Researchers from the Babraham Institute, Cambridge and Sapienza University, Rome, have been discovered a group of genes and genetic switches associated with age-related brain deterioration. The results of the work, published on March 5, 2018 in Aging Cell, demonstrate that a changes to one of these genes, called Dbx2, could prematurely age brain stem cells, slowing their growth.
Scientists from the Diabetes Research Institute (DRI) at the University of Miami Miller School of Medicine have confirmed the existence of stem cells within the human pancreas that can be activated to produce glucose-responsive beta cells. The results, published on February 27, 2018 in Cell Reports, are of great importance for the development of regenerative cell therapy for the treatment of diabetics.
A study conducted by scientists from the University of Cambridge, UK, demonstrated that transplantation of brain stem cells derived from reprogrammed skin cells helps to reduce inflammation and repair damage caused by multiple sclerosis. The results, published on February 22, 2018 in Cell Stem Cell, are an important step in the development of individual treatment of central nervous system (CNS) diseases based on the patient's autologous cells.
Scientists from the University of York, UK, have shown that changing the structure of sugar chains located on the surface of mesenchymal stem cells could help promote bone growth in the body. The discovery, published on February 14, 2018 in the Journal of Cell Science, can be an important stage in the development of methods for treating of osteoporosis, a disease characterized by fragile and weak bones.
A research team at the University of California, Los Angeles (UCLA), USA has created hematopoietic stem cells by incorporating a gene in their DNA that allows the body to produce immune cells that can detect and destroy HIV-infected cells. The results of the research are published in the journal PLOS Pathogens.
Researchers from the Gladstone Institutes, USA, managed to obtain stem cells from skin cells, by activating just one gene in the cells using CRISPR technology. The innovative method, published on January 18, 2018 in Cell Stem Cell, offers a potentially simpler technique to produce the valuable cell type and reveals important information about the process of cellular reprogramming process.