An international team led by scientists from the University of California, San Diego, in an article, published May 9, 2018 in Science Translational Medicine, describes a successful grafting induced pluripotent stem cell (iPSC)-derived neural precursor cells into pigs with spinal cord injury without immunosuppression.
Researchers from the University of Washington School of Medicine in Seattle, US, have developed a new robotic system to automate the production of human mini-organs derived from stem cells. The ability to rapidly, mass-produce organoids promises to expand their use in basic research and drug discovery. The results were published may 17, 2018 in Cell Stem Cell.
Scientists from the Massachusetts Institute of Technology (MIT), US, found that fasting significantly improves the regenerative function of stem cells in both aged and young mice. The results, published on May 3 in Cell Stem Cell, will help restore intestinal cells in cancer patients undergoing chemotherapy, as well as in aged people suffering from age-related diseases.
Salk Institute researchers demonstrated in mice that hemophilia B can be completely cured with one single injection of stem cells-derived healthy hepatocytes that can produce missing clotting factor. The results of the study, published on May 1, 2018 in Cell Reports, could drastically change the lives of patients with hemophilia B and could pave a new path toward similar methods of treating diseases caused by genetic disorders.
An international team of scientists from Belgium and the United States are studying revealing previously unknown details of the reprogramming of adult cells into induced pluripotent stem cells (iPSCs). They found that female and male cells behave differently after being reprogrammed into stem cells, and this is due to a different number of X chromosomes. The results of the work were published on April 19, 2018 in Stem Cell Reports.
A team of scientists at Washington University in St. Louis, US, has developed a method for creating tissues of the nucleus pulposus of the spine from induced human pluripotent stem cells (hiPSC). A study, published in Stem Cell Research & Therapy, can help in developing methods for treating chronic pain in the neck and back.
According to a study conducted at the Stanford University School of Medicine, liver stem cells expressing high levels of telomerase restore the organ during normal cellular metabolism or tissue damage. Understanding this process plays an important role in the treatment of diseases such as cirrhosis or liver cancer. The results of the work were published on April 4, 2018 in Nature.
Bioengineers from Rice University, US, have successfully used gene editing technology to correct mutations in stem cells derived from the peripheral blood of patients with sickle cell disease. The results of the study were presented at the annual meeting of the American Association for the Advancement of Science (AAAS) in 2018 in Austin, Texas.
Scientists from the University of Queensland, Australia, have discovered a new type of dual stem cells (SC) that can produce tissues with integrated blood vessels. The results of the study are published in Stem Cell Reports.