Treatment of pancreatic necrosis with stem cells

In 2012 the ministry of Health defense in Ukraine officially approved the method of stem cell therapy for many diseases such as pancreatic necrosis.

Pancreatic necrosis is a severe disease associated with inflammation an acute pancreatitis. In this condition, ferments secreted by gland accumulate in duodenum resulting in tissue distruction (self-digestion).Exuded enzymes and toxins can hit into the blood stream and cause a serious damage for heart, lungs and leaver. Interestingly, this disease is rarely observed in people who drink a lot of alcohol.

However, pancreatic necrosis can occur in any individual but it is more dangerous for those who eat lots of fat and drink alcohol at some parties or celebration. Such symptoms as quickened pulse, pain in left upper quadrant and navel area, general sickness and even vomiting are visible 2-3 days after event.

Cholelithiasis, poisoning, various injures and virus infections may also lead to pancreatic necrosis. The disease is typical for people 30-60 years old and more frequent for women than men.
Currently pancreatic necrosis is treated with surgery .

The main risks here are postsurgical complications such as foul processes, pancreatic shock, septic shock that lead to 33-86% mortality.

The Institute of Cell Therapy of Coordination Center of organs, cells and tissues transplantation of MHDU cooperatively with surgeons of National Academy of post degree education of Shupik have applied the method of pancreatic necrosis treatment with cord tissue and transplantation of cord blood stem cells.

The essence of method is an implantation of prepared crioconserved cord tissue enriched with bioactive substances that obliterate open canals of pancreas, into necrosis zone after the surgery. As a result, cystic lesion does not form. Second day after the surgery the implant is removed using drainage system. At the same time, an intravenous administration of cord blood stem cells is carried in small dozes daily during 5-7 days. It results in reparative regeneration processes, so the patient spends less time in clinics after the surgery.

The method of stem cells was applied to more than 20 patients. The mortality decreased to zero. For 6 months after the surgery cystic lesions were not observed. One patient untreated with stem cells have developed a respiratory distress with saturation decrease to 50%. In reanimation department this patient was administered with cord blood stem cells once a day during 5 days.

The breath function and respiratory circulation recovered. Patient left the hospital without any complications 10 days after the first administration of cord blood stem cells.